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Advances in Coenzyme Q10 – the rise of Ubiquinol

In Health and Nutrition by stephen.eddyLeave a Comment

Studies have shown that, as we age, the concentration of CoQ10 in the body decreases. Although we may be more familiar with CoQ10, there have been some significant advances in Ubiquinol which may make it a game-changer for promoting energy naturally in our bodies.


Fatigue and low levels of energy are quite normal considering the busy lifestyles we choose to lead. Factors that may contribute to low levels of energy in the body include diet, lack of exercise, and insufficient quality sleep per night. While many are tempted to turn to coffee or energy drink as an alternative, it is the more natural ingredients that are more beneficial for our body when it comes to raising our energy levels.

One of these natural ingredients is Ubiquinol. This is a vitamin-like substance that exists naturally in the cells of the human body. Ubiquinol is the reduced and active form of CoQ10, which we know has been used in skin care products as well as to support heart health.

The primary role of Ubiquinol is for efficient energy production in the mitochondria, known as the ‘power producer’ of all body cells. Ubiquinol is also considered a powerful antioxidant that helps protect and soak up oxidative stress caused by excess free radicals. Free radical damage occurs within our cells as we age. Oxidative stress occurs as a result of the body’s inability to effectively combat free radical damage. These may be enhanced by factors such as environmental toxins, a poor diet, and excessive amounts of stress. Ubiquinol is beneficial in that it assists in providing antioxidant support and helps to maintain a healthy heart and vascular system.

Although we may be more familiar with CoQ10, there have been some significant advances in Ubiquinol which may make it a game-changer for promoting energy naturally in our bodies.To explain why, CoQ10 is currently available in two forms in our bodies. Ubiquinone is the traditional form that is oxidised, while Ubiquinol is the reduced and active form. More than 95% of the total CoQ10 found naturally in the plasma of a young, healthy body is in the Ubiquinol form (1). Ubiquinone must be converted to Ubiquinol in the body before it can be utilised, whereas Ubiquinol does not have to undergo any conversion process, thus is more readily available for its multitude of benefits. It is for this reason that scientists are continuing to study the wide range of benefits of Ubiquinol.

Studies have shown that, as we age, the concentration of CoQ10 in the body decreases, and the efficient conversion of Ubiquinol may also become impaired. Insufficient levels of Ubiquinol in the body may lead to reduced energy production in our bodies.

The energy conversion process is a key part of our normal bodily functions. Ubiquinol is considered a vital part of this process. Therefore, Ubiquinol is found to be concentrated naturally in organs that require the most energy, including the heart, liver, muscles and kidneys.

Here are three of the main health benefits associated with Ubiquinol:

1.  Helps maintain a healthy heart and vascular system

Research has shown that Ubiquinol assists in providing support for the heart by helping to  maintain a healthy heart and vascular system. In addition, it provides cholesterol support by helping to maintain healthy LDL cholesterol levels in healthy people (2), (3)

2.  Energy production

A double-blind placebo-controlled study, based on 100 German athletes, found enhanced physical performance with six weeks of daily supplementation with 300mg of Ubiquinol. (4)

3.  Support for statin use

Statins are cholesterol lowering drugs, with common side-effects which may include muscle weakness and pain. Studies have indicated that Ubiquinol may help minimise the negative side-effects associated with taking these statins . (5)

Ubiquinol can be found naturally in a number of foods such as tuna, spinach, garlic, and oranges. However levels of Ubiquinol may not be sufficient enough to provide the required energy needed to power your body.



(1) Wada H et al. Redox status of coenzyme Q10 is associated with chronological age. JAGS 2007;55:1141-42.

(2) Langsjoen PH & Langsjoen AM. Supplemental ubiquinol in patients with advanced congestive heart failure. Biofactors 2008;32:119-28.

(3) Ibid [2].

(4) Alf D, Schmidt M & Siebracht SC. Ubiquinol supplementation enhances peak power production in trained athletes: a double-blind, placebo-controlled study. Jour Int Soc Sport Nutr 2013;10(24).

(5) Zlatohlavek L et al. The effect of coenzyme Q10 in statin myopathy. Neuroendocrinol Lett 2012;33(2):98-101.


Stephen Eddey is a qualified Nutritionist and Naturopath and is the Principal of Australia’s longest established natural medicine college, Health Schools Australia. He has completed a Bachelor of Complementary Medicine as well as a Masters in Health Science and PhD in Nutritional Medicine.

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